Chelsea striker Didier Drogba suffered suspected knee ligament damage in the Champions League goalless draw with Romanian side CFR Cluj on Wednesday.
Drogba, who has just returned from knee injury, left the stadium on crutches and is set to have a scan on Thursday.
Chelsea manager Luiz Felipe Scolari also said John Terry and Alex suffered knocks in the game.
But he said Ashley Cole will be fit for the weekend after missing the game against Cluj with a back problem.
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Scolari said: "I don't know now what the possibilities I have for Sunday are, maybe after Thursday I have a chance to say something more.
"I didn't see the challenge on Drogba. Injuries come in training and on the pitch. This is normal for players."
BBC 5 Live's Simon Brotherton was in Romania and believed the injuries would test a Chelsea squad which was smaller than previous seasons.
"Injuries are starting to mount up," he said.
"Drogba was stretchered off with ligament damage, Ashely Cole was left out with lower back pain, John Terry was holding his back by the end of the game and they were already without Deco, Essien, Carvalho and Joe Cole.
"The squad, smaller this season, may well be stretched and we're only just into October."
Brazilian coach Scolari was not too disappointed with the result against a side making their debut in the group stages of the Champions League.
"We didn't play well, but one point is better than zero points," he added.
"They beat Roma, they are confident, they're playing at home and they wanted to show to the people they are very good.
"Cluj were confident, they wanted to prove something. Maybe they will have a problem in their next game because they ran for 95 minutes."
"We knew this and we prepared but we missed one or two times in front of goal.
"But in the end I am happy with one point because Didier is out, Terry for 15 minutes played with problems, Alex played 15 minutes with problems."
(BBC)
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